Name: NO-Bis(trimethylsilyl)acetamide Material Safety Data Sheet
Synonym: BSA; bis(trimethylsilyl)acetamide
CAS: 10416-59-8

Section 1 - Chemical Product
MSDS Name: NO-Bis(trimethylsilyl)acetamide
Synonym: BSA; bis(trimethylsilyl)acetamide.
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
10416-59-8 NO-Bis(trimethylsilyl)acetamide 100 % 233-892-7
Hazard Symbols: XN F
Risk Phrases: 10 22

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Flammable. Harmful if swallowed.Water-Reactive.
Potential Health Effects
Eye:
Causes severe eye irritation.
Skin:
Causes skin irritation.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation:
Causes respiratory tract irritation.
Chronic:
May cause cancer according to animal studies.

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use carbon dioxide or dry chemical. DO NOT USE WATER!
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Scoop up with a nonsparking tool, then place into a suitable container for disposal.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Do not get on skin or in eyes. Avoid ingestion and inhalation.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Appearance: clear to light yellow
Odor: None reported.
pH: Not available.
Vapor Pressure: 18 mbar @ 50 C
Viscosity: Not available.
Boiling Point: 71.0 - 73.0 C
Freezing/Melting Point: 24 deg C
Autoignition Temperature: Not applicable.
Flash Point: 107 deg F ( 41.67 deg C)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: >80 C
Solubility in water: Decomposes in water.
Specific Gravity/Density: 0.83
Molecular Formula: C8H21NOSi2
Molecular Weight: 203.3241

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
High temperatures, mechanical shock, incompatible materials, ignition sources, exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, and moist air or water.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen, silicon oxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 10416-59-8: AK3000000 LD50/LC50:
Not available.
Carcinogenicity:
NO-Bis(trimethylsilyl)acetamide - IARC: Group 3 carcinogen (listed as ** undefined **).
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Keep away from ground water, waters and drains.

Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.

Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: FLAMMABLE LIQUID, NOS
Hazard Class: 3
UN Number: 1993
Packing Group: II
IMO
Shipping Name: FLAMMABLE LIQUID, NOS
Hazard Class: 3
UN Number: 1993
Packing Group: II
RID/ADR
Shipping Name: FLAMMABLE LIQUID, NOS
Dangerous Goods Code: 3
UN Number: 1993

Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN F
Risk Phrases:
R 10 Flammable.
R 22 Harmful if swallowed.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 10416-59-8: 1
United Kingdom Occupational Exposure Limits
CAS# 10416-59-8: OES-United Kingdom, TWA (listed as ** undefined
**): total inhalable dust: 6 mg/m3 TWA; respirable dust: 2.4 mg/m3
TWA
Canada
CAS# 10416-59-8 is listed on Canada's NDSL List.
CAS# 10416-59-8 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 10416-59-8: Not available.
US FEDERAL
TSCA
CAS# 10416-59-8 is listed on the TSCA inventory.